Do Typewriter Eraser Brushes Exist?
The image depicts round objects that are typewriter erasers, which were packaged with a little brush. The erasers were composed of supple materials such as rubber, frequently combined with fine abrasives. This mixture was created to eliminate typewriter ribbon marks or ink from paper, which was the main way to fix errors in a typewritten text before digital editing or white-out were introduced.
After removing a letter or word from the paper, the tool’s tiny brush was used to carefully brush away the eraser residue that remained on it. During the era when typewriters dominated both the business and literary domains, these instruments were indispensable for upholding orderly and polished work.
A Moment in Time: The Days When Eraser Brushes Were Crucial
Typewriter eraser brushes were as ubiquitous in the early to mid-1900s as correction fluid or computerized backspace buttons are in the modern era. Because typing errors were unavoidable no matter how careful one was, every typist had one on their desk. With the use of these tools, errors might be fixed without having to start over with a completely new page.
Several sheets of paper could have to be fixed due to the widespread use of carbon paper for copying back then. Eraser brushes worked well to erase the incorrect marks without causing any tearing of the fragile material.
The Era of Typewriters’ Decline
Typewriters were quickly rendered obsolete with the advent of word processors and subsequently personal computers. As instantaneous editing became possible with digital text, the necessity for such specialized erasers diminished. These erasers have become rare artifacts from a bygone era when typing was a talent and an art.
The world of writing and editing has changed so much that seeing one of these erasing brushes now brings back memories for those who used them. There has never been a truer statement than “times have changed,” particularly when contrasting the difficulties of erasing a typewritten text with the simplicity of the undo button on contemporary technology.
A Unique Collectible
In the modern era, typewriter eraser brushes are prized collections. They are valued for their simplicity and efficacy by vintage enthusiasts and fans of retro office supplies. As a tribute to the inventiveness of earlier generations and the unusual equipment that formerly supported daily chores, they may appear out of place in a world where digital devices rule.
In summary, from indispensable to outdated
The image’s tools could appear strange or even antiquated to individuals who have never used a typewriter. Older generations, however, associate them with the constant presence of an eraser brush next to the keyboard, the scent of ink ribbons, and the steady clacking of typewriter keys. It is undeniable that times have changed, and like many advancements, what was once indispensable now quietly lies in the annals of history.
We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth
The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.
A dental breakthrough
While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.
A bit of science
The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.
As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.
On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.
BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.
“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.
The first results
Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.
“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.
Fully regrown frontal teeth in ferrets
The next steps
Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontia, a genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.
Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.
“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”
So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.
Preview photo credit KyotoU_News / Twitter
Leave a Reply